almost impossible; very difficult, especially of physical movement.
[It is] almost impossible [for] you to be yessed by me, because already he talked to me about that thing first.
It is very difficult for me to say yes to you, because he already talked to me about that thing first.
When a left-handed person writes, like [it is] plainly almost impossible.
When a left-handed person writes, it seems very difficult.
[It is] impossible [for] you to be carried by me, this me is shouldering a pillow.
It is impossible for me to carry you because I am carrying a pillow. [Irony.]